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  • Alejandro Penaloza-Vazquez
  • Patricia Rayas-Duarte



Project TitleShelf stable probiotics for animal nutrition enhancement
Track Code2014-031
Short DescriptionNone
Tagsanimal science
Posted DateJul 5, 2016 4:56 PM


Alejandro Penaloza-Vazquez
Patricia Rayas-Duarte


Scott Davis


Most animal diets are rich in fiber and phytate, which impairs the absorption of nutrients such as iron, zinc, calcium, protein, and other minerals. As a result, micronutrient deficiencies often arise in animals, hindering their proper growth. To combat the negative effects of phytate, commercial feeds incorporate phytase additives to increase digestion and weight gain in younger animals. However, livestock and poultry feeds currently derive these additives from vegetative organisms which do not hold a long shelf life, due to their low thermostability and specificity. Therefore, there is still a need to improve animal diets by developing a more durable, long-lasting feed that can effectively counter the negative effects of phytate and fiber.


OSU researchers have developed a robust probiotic mixture with improved thermostability and specificity than current commercial feed. This invention enhances the nutritional value of animal and human diets by increasing availability of nutrients and protecting against specific pathogens. This mixture displays specific enzyme and antimicrobial activity as well as bile acid resistance. Unlike conventional nutrition solutions, this mixture does not require expensive scale-up, as it successfully maintains shelf life while utilizing local and natural resources.

Potential Applications

  •  Animal feed industry
  • Human food industry

Main Advantages

  •  Long shelf life
  • Inexpensive scale-up
  • Uses natural and local resources
  • Increased thermostability
  • Increased specificity

Stage of Development

Proof of Concept stage and PCT filed. 

Contact Information

Please contact OSU’s Technology Development Center at for more information.

Intellectual Property

Patent Number Issue Date Type Country of Filing
PCT/US2015/025983 None Utility United States