Innovation Sphere


  • Divya Jaroni
  • Pushpinder Litt



Project TitleBacteriophages to control Shigatoxigenic Escherichia coli
Track Code2015-037
Short DescriptionNone
Tagsanimal science
Posted DateSep 21, 2016 11:50 AM


Divya Jaroni
Pushpinder Litt


Scott Davis


Shigatoxigenic E. coli (STEC) is a major contributor to one in six Americans becoming sick due to a foodborne illness each year. Current methods often employ harsh chemical interventions to reduce STECs and are not optimally effective. From 2009-2013, 35% of 75 foodborne illness outbreaks in ground beef were due to STECs. Clearly there is a need for novel methods to further reduce STEC outbreaks and illness effectively.


Divya Jaroni Ph.D., at Oklahoma State University has developed a system to identify novel bacteriophage that are effective either singly or in combination against multiple strains of STECs, including O157, O45, O121, O145, O111 and O26. Dr. Jaroni has already isolated phages that have high lytic activity across multiple STEC strains, and are thermostable, pH stable and have a long shelf life. This technology will provide a natural and safe alternative to current industry-pathogen-control-strategies.

Potential Applications

•       Food equipment sterilization

•       Food sterilization

•       Natural food preservative

•       Medical industry

Main Advantages

•       Thermostable

•       Ph stable

•       Storage stable at -80, -20 and 4 degrees

•       Strong inhibition of STECs

•       High lytic activity

•       Can reduce biofilm formation

Stage of Development

Proof of concept.  

Contact Information

Please contact for more information.

Intellectual Property

Patent Number Issue Date Type Country of Filing
None None Other Patent None